Interactive Karyotype Activity

: Using a standardized notation, students write their diagnosis (e.g., 47, XY, +18 for Edward syndrome). They then answer follow‑up questions, such as: What are the clinical features of this condition? What is the long‑term prognosis? How does non‑disjunction during meiosis lead to this disorder?

Design Considerations

Scissors, glue or tape, and the printed chromosome sheets provided below. Interactive Karyotype Activity

: Do not just give students random chromosomes. Give them a "patient file" with symptoms (e.g., "Patient is a 14-year-old girl experiencing stunted growth"). This builds empathy and context. : Using a standardized notation, students write their