Juq-123 ((full)) Jun 2026
Now, I will write the article. Decoding JUQ-123: An In-Depth Look at Madonna's Business Trip Overnight Stay Series
Biochemical profiling revealed that JUQ-123 inhibits JAK2 with an IC50 of 12.4 nM, showing >50-fold selectivity over other JAK family members (JAK1, JAK3, TYK2). In the USP7 Ub-Rho assay, JUQ-123 demonstrated an IC50 of 35.2 nM, while showing minimal activity against other DUB family members (USP1, USP5, USP10), confirming its dual-target specificity. JUQ-123
